Using ELISPOT to Expose False Positive Skin Test Conversion in Tuberculosis Contacts

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Using ELISPOT to Expose False Positive Skin Test Conversion in Tuberculosis Contacts

BACKGROUND Repeat tuberculin skin tests may be false positive due to boosting of waned immunity to past mycobacterial exposure. We evaluated whether an ELISPOT test could identify tuberculosis (TB) contacts with boosting of immunity to non-tuberculous mycobacterial exposure. METHODOLOGY/PRINCIPAL FINDINGS We conducted tuberculin and ELISPOT tests in 1665 TB contacts: 799 were tuberculin test ...

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ژورنال

عنوان ژورنال: PLoS ONE

سال: 2007

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0000183